Boost Testosterone and Suppress Estrogen Levels Naturally

For men who choose not to (or are advised not to) use hormone replacement therapy, nutrients can play a vital role in a comprehensive program designed to reduce the impact of aging on sex hormone production and metabolism. The following is a list of nutrients that are part of Life Extension's comprehensive male hormone restoration program.

Essential nutrients for optimal testosterone production:

Zinc:
This mineral is involved in almost every aspect of male reproduction, including testosterone metabolism, sperm formation, and sperm motility (Ali et al 2005). A prime example of the usefulness of zinc was illustrated in a study of 37 infertile men with decreased testosterone levels and associated low sperm counts (Netter et al 1981). The men were given 60 mg of zinc daily for 45-50 days. In the majority of patients, testosterone levels significantly increased and mean sperm count rose from 8 million to 20 million. Some men require higher levels of zinc to adequately suppress aromatase.

DHEA:
DHEA is an important hormone that tends to be depleted steadily with age (Basar NM et al 2005). A 2006 study assessing DHEA supplementation in men of average 65 years of age found that the men experienced significant increases in testosterone and significant decreases in low-density lipoprotein (Martina et al 2006).

Tribulus:
Tribulus terrestris, also known as puncture vine, contains the active ingredient protodioscin, which is reportedly converted to DHEA in the body (Adimoelja A 2000). This DHEA-boosting activity may account for puncture vine’s reputation as an aphrodisiac in its native Europe and Asia. Animal studies appear to confirm the ability of tribulus to improve sexual function (Gauthaman et al 2003; Milasius et al 2009).

Antioxidants:
One reason testosterone production may decline with advancing age is oxidative damage in the tissues that produce testosterone. A study examining the role of antioxidants in male hormone imbalance in aging men noted that antioxidant supplements (including vitamins A and E, zinc and selenium) all supported testosterone production (He et al 2005). 

Natural products keep aromatase and/or sex hormone-binding globulin (SHBG) in check:

Chrysin:
The bioflavonoid chrysin is a natural aromatase inhibitor (Kellis et al 1984). Bodybuilders have used chrysin as a testosterone-boosting supplement, because it minimizes the conversion of testosterone to estrogen. Although chrysin has low oral bioavailability (Walle et al 2001), its bioavailability may be significantly enhanced by co-administration with the black pepper extract, piperine, thus enhancing its actions as an aromatase inhibitor (Srinivasan et al 2007).

Quercetin:
One study showed that red wine inhibits aromatase, thus inhibiting the conversion of testosterone to estrogen. The study attributed this effect to the quercetin and other ingredients (Eng et al 2002).

Nettle root:
Lignans contained in nettle root extract may help prevent the binding of sex hormone-binding globulin to testosterone. This may help ensure that free testosterone is available for promoting male vitality and youthful sexual function (Anon 2007, Chrubasik et al 2007). Nettle root extract is used extensively, either incombination with saw palmetto (Lopatkin 2005) or by itself (Safarinejad 2005) for relief of BPH symptoms.

Fish oil:
A study examined how the essential fatty acids EPA and DHA affected SHBG levels in men 43 to 88 years of age (Nagata et al 2000). After controlling for other variables, the researchers concluded that both EPA and DHA decreased levels of SHBG in middle-aged and elderly men.

Protein:
While adequate protein consumption is vital to maintaining muscle mass, it is also important in maintaining testosterone levels. A study examined the relationship between diet and SHBG, and found that diets low in protein in men 40-70 years old may lead to elevated SHBG levels and consequently decreased testosterone bioactivity (Longcope et al 2000).

Natural products to support sexual function:

Muira Puama:
Muira puama, Ptychopetalum olacoides, grows in the Amazon region of Brazil. It is considered an aphrodisiac and an effective treatment for impotence. It has been studied by Jacques Waynberg (Waynberg 1990), a prominent medical sexologist at the Institute of Sexology in Paris. In one of his studies, men with loss of libido received 1.5 grams/day of muira puama for 2 weeks. 62% rated the treatment as having a dynamic effect, and 52% with erectile dysfunction rated the treatment as beneficial. In another study, muira puama treatment was given to 100 men, aged 18 years or older, with impotence and/or loss of libido. A significantly Increased frequency of intercourse was reported in 66% of the men. Of the 46 men who complained of loss ofdesire, 70% reported libido intensification. The stability of erection during intercourse was restored in 55% of men, and 66% of men reported a reduction in fatigue. Other reported beneficial effects included improved sleep and morning erections.

Maca:
Maca has been used among indigenous people in the Andes region for centuries. It is a reputed aphrodisiac and fertility enhancer. Peruvian researchers conducted a randomized, placebo-controlled double-blind study on a small group of men aged 21-56. Results showed that, versus placebo, maca improved subjective reports of male sexual desire. Subjects consumed either 1,500 mg or 3,000 mg of maca, or placebo, for three months. After eight weeks, improvements were noted in sexual desire among the subjects who consumed maca (Gonzales et al 2002).

L-Carnitine:
L-Carnitine is an amino acid derivative that may be more active than testosterone in aging men who have sexual dysfunction and depression caused by an androgen deficiency (Cavallini G et al 2004). Both testosterone and carnitine improve sexual desire, sexual satisfaction, and nocturnal penile tumescence, but carnitine is more effective than testosterone in improving erectile function, nocturnal penile tumescence, orgasm, and general sexual well-being. L-Carnitine was also more efficacious than testosterone for treating depression (Cavallini G et al 2004).

Natural products to support prostate health

Indole-3-carbinol (I3C):
I3C protects against dangerous estrogen metabolites and subsequent prostate cancer. An adequate intake of I3C, through vegetables such as broccoli, Brussels sprouts, and cabbage, or via supplements, may be very helpful for aging men in both keeping undesirable estrogen metabolites such as 16-alphahydroxyestrone in check and decreasing their riskof prostate cancer. Studies have demonstrated that I3C increases the ratio of 2-hydroxyestrone to 16-alpha-hydroxyestrone. For men, this very well might mean a decrease in prostate cancer risk (Sepkovic et al 2001, Bradlow 2008). In a study that examined the association of prostate cancer risk with estrogen metabolism, the authors said, “results of this case-control study suggest that the estrogen metabolic pathway favoring 2-hydroxylation over 16-alpha-hydroxylation may reduce risk of clinically evident prostate cancer” (Muti et al 2002).

Pygeum:
A bark extract from the native African cherry tree, Pygeum africanum has been used in Europe to treat BPH since 1960, and is currently the most commonly used therapeutic agent for this condition in France (Buck 2004). One theory for the anti-BPH action of pygeum involves the conversion of testosterone to dihydrotestosterone (DHT), a potent testosterone metabolite that may exacerbate BPH, via the enzyme 5-a-reductase (Wilt et al 2002). A recent study identified that N-butylbenzene-sulfonamide (NBBS) was isolated from P. africanum as a specific androgen receptor (AR) antagonist. NBBS inhibits AR- and progesterone receptor (PR)- mediated transactivation, as well as endogenous PSA expression and growth of human prostate cancer cells (Papaioannou et al 2009).

Saw Palmetto:
In Europe, saw palmetto (Serenoa repens) has been used extensively as a drug for reducing symptoms of (BPH). Saw palmetto has multiple mechanisms of action: inhibition of 5-alpha-reductase; inhibition of DHT binding to the androgen receptor; reduction of the inflammatory component of prostate growth (by inhibiting COX-2 and an enzyme called 5-lipoxygenase); induction of apoptosis and inhibition of prostate cell proliferation (Debruyne 2002; Goldmann et al 2001; Paubert-Braquet et al 1997; Vacherot et al 2000). Its clinical benefits for prostate enlargement include reduced nocturnal urinary urgency (Pavone et al 2010), decreased residual urine volume in the bladder (Giannakopoulos et al 2002), and less discomfort from urination symptoms (Mantovani 2010).

Testosterone and Prostate Cancer: The Myth

For more than 6 decades, the medical establishment erroneously conjectured that testosterone replacement therapy increases one’s risk of developing prostate cancer. This fear has made it standard practice for physicians to deprive hypogonadal male patients of testosterone replacement that could otherwise provide them with a world of cardiovascular, musculoskeletal, cognitive, metabolic and other health benefits, as discussed above.

Remarkably, though, it appears that, in most cases, the opposite is true—lower levels of endogenous testosterone present a greater risk of prostate cancer than higher levels (Morgentaler 2009). A review of data from the National Institutes of Health revealed that, in men of advancing age, “high testosterone levels are not associated with an increased risk of prostate cancer, nor are low testosterone levels protective against prostate cancer” (Morgentaler 2006).

A collaborative review of 18 prospective studies compared serum concentrations of androgen and estrogen in 3,886 men with prostate cancer with those in 6,438 healthy controls. The results showed no significant associations between the risk of prostate cancer and sex hormone levels (Roddam et al 2008).

In more than 500 men diagnosed with prostate cancer (followed over a mean of 8.7 years), high androgen levels were actually associated with a decreased risk of aggressive prostate disease, compared with no change in the risk of non-aggressive disease. Overall, levels of any steroid hormones (except estradiol) were not correlated with the risk of aggressive prostate cancer (Severi et al 2006).

Abraham Morgentaler, an associate clinical professor at the Harvard Medical School, in his book Testosterone for Life,convincingly makes the case for the benefits and safety of high testosterone vs. the dangers of low testosterone. He also goes back to the original 1941 Nobel Prize-winning research (Huggins et al 1941) about testosterone and shows how these data have been misinterpreted and unquestioned for over 70 years.

What You Need to Know: Optimizing Testosterone Levels in Aging Men

  • Testosterone, the chief male hormone, is essential for libido and erectile function, and plays a crucial role in mood, energy, bone health, and body composition.
  • Testosterone levels decline with age, usually beginning in a man’s mid-30s. Diminishing testosterone levels have been linked with disorders such as depression, fatigue, obesity and cognitive decline.
  • Low testosterone in men is strongly associated with metabolic syndrome, and may be a risk factor for type 2 diabetes and cardiovascular disease.
  • Restoring testosterone to youthful levels offers men a wealth of health benefits, including benefits for heart health, body composition, mood, and memory.
  • Bioidentical testosterone has not been found to have adverse effects on the healthy prostate gland—in fact, it may help improve prostate symptoms in men with low-normal testosterone levels. Testosterone therapy is contraindicated in men with prostate cancer.
  • Regular blood testing can help you and your physician decide if testosterone therapy is right for you. Optimizing testosterone levels requires a multi-pronged approach that includes optimal diet, proper nutrition, nutritional supplements, exercise, and bioidentical testosterone.

Testosterone Replacement Therapy

Edited By Ross B. Macdonald
 

The first sign of low Testosterone(T) is a loss of libido which may be followed by erectile dysfunction (ED). There are five basic causes of low T: Conversion of T to estrogen by a process called aromatase , especially in men with excess belly fat; pituitary gland is failing to produce enough luteinizing hormone (LH); T is being bound by SHBG (Sex Hormone Binding Globulin); Testicles have lost their ability to produce T and finally abnormally low DHEA.

The next step after deciding to use T replacement therapy is a blood test. The test should include and results be between:

Total T (700-900 ng/dL)
Bioavailable T (with in normal range)
Free T (20-25 pg/mL)
Estradiol (E2) (20-30 pg/mL)
LH within normal range
SHBG—( important !!) within normal range
DHEA-S (350- 400 ug/dL)

The results of these tests will help determine the proper course of treatment. (Check with a doctor that is knowledgeable about this subject first)

Examples from Life Extension Foundation:

Low Free T – High Estradiol—Mid Total T-= aromatase ( see appendices for discussion)
High Total T –Low Free T— = Free T being bound by SHBG
Low Total T-- = pituitary gland not producing enough LH
Low Total T—low LH = testicles not producing enough T
Abnormally LOW DHEA-S

There are several vitamin/supplements recommended for T therapy which are listed at the bottom of this report.

MEDICAL TESTOSTERONE REPLACEMENT THERAPY is available in 5 ways:

Injections, Pills, Gels/Creams, Pellets and Patches.

The general consensus among doctors is apparently:

Injections work well for short time periods as they give a boost but then drop off quickly. They are not consistent. Injections are needed about every two weeks by a doctor or yourself.

Pills are easy to use but are absorbed by the stomach and liver rapidly. The effect is therefore minor.

Pellets require surgery by a doctor periodically, and this is expensive.

Patches work well but can cause skin rashes and be uncomfortable or embarrassing as they are worn near the scrotum.

Gels/Creams are the most highly recommended especially the GEL. A 50 mg daily dose is applied to the upper area of the body (do not rub in). Gels produce a serum profile which varies throughout the day as it does normally in a healthy young man. GELS are better at treating sexual dysfunction than are injections etc. Gels are more absorbable than Creams and the T sinks into the skin with in an hour. Put the gel on the inside of forearms and rub them together or rub the forearms up and down against your upper sides. Do not rub with the palms of your hands.

“The constant variability of serum androgens provided by the Testosterone gels mimic the hormones of a young man; the stable daily level provided by injections mimic the hormones of an old man, those of implanted pellets mimic the hormones of no man”. Dr. John Crisler.

Apendices:

AROMATASE solutions: The primary thing to do to stop the conversion of Testosterone into Estrogen is To LOSE fat, especially belly fat (adipose fat). A supplement known as Calcium D Glucarate can help.

If, however, the blood tests continue to show a possible high conversion rate then the medicine to use is ARIMIDEX.(available without a prescription in Mexico). Start with 1/2 mg twice a week. Then after a month get another blood test. If it is still high increase dose to 3 times per week or more if necessary as blood tests show. ARIMIDEX is the drug used to control excess Estrogen in women's breast cancer.

Life Extension Foundation recommended vitamins /supplements for low testosterone: Chrysin, Piperine, Zinc, Muira Puama, Quercetin, Fish Oil, Nettle Root, Pygeum, and DHEA. For boosting sexual function: Selenium, Vitamins E and D, Protein, Acetyl L Carnitine, Tribulis and Maca Extract.

REFERENCES for the MENS’ HEALTH SERIES

Life Extension Foundation : various articles from their magazines over the last 5 years.
Testosterone Replacement Therapy, Dr. John Crisler.
Testosterone for Life, Dr. Abraham Morgenthaler, Harvard Medical School
Un of Texas Health Science Center
Stanford Medical School
Dr. Michael Miller, Professor, Un of Maryland
N.E. Journal of Medicine
Dr. Phillip Lee Miller
Journal of the American Heart Assoc.
Harvard Medical School Publications.
Johns Hopkins Un. Medical School-- BPH

BPH and uses of Cialis

There are too many factors in BPH causing urinary problems among older men to  discuss in detail here.* BPH is NOT cancer but an enlargement of the tissue and muscle in the prostate which puts pressure on the urethea causing weak, frequent and sometimes painful urination, especially at night. This is common in men as they age past 50 and more prevalent as the years pass.

SYMPTOMS:

ED (erectile dysfunction)

Need for frequent and urgent need to urinate

Weak flow and difficulty starting

Overweight men are more likely to develop BPH and obese men are 3.5 times more likely according to John Hopkins Hospital, (particularly those with abdominal fat).High blood sugar above 110is also a factor. Probably a good percentage of the men reading this article have BPH as I do.

Some remedies:

Saw Palmetto has been a standard for years but has some positive but also some negative research results. Worth trying especially if you add Nettle Root to the daily dose.

Then you can go on to Beta Sitosterol and even further to Finasteride(but this one while working well on BPH has negative effects on sexual function).

Also, in a study, men who took beta-sitosterol experienced greater improvements on two standardized assessments of prostate/urinary symptoms than men who took a placebo.  .”  LIFE EXTENSION FOUNDATION ADVISORY   May 22, 2016.

C

The problem is there is no generic Cialis made in Mexico and the 5 mg brand is 75 pesos per pill. If you are interested I have a quality source of 10 and 20 mg generic Cialis at a greatly reduced cost. Email me for information. For BPH just use a pill cutter to halve the 10mg pill. I have used Cialis for 2 months AND it works!!

Extendinglives@gmail.com

There is a 63 page report from Scientific America Magazine and Johns Hopkins on BPH available by emailing me

Ross Macdonald

415 1535378

Testosterone And Your Heart

TESTOSTERONE and YOUR HEART

Sudden cardiac arrest (SCA) is usually caused by an electrical disruption in the heart’s pumping action. Research in 

2014 revealed that lower levels of testosterone or higher levels of estrogen in men were associated with a greater risk 

of SCA .It is necessary to have blood levels of testosterone and estradiol (estrogen) checked to discover if 

testosterone is being converted to estrogen.

Each day in the USA there are about 1,000 SCA cases and the recovery rate is some 5%. Magnesium and Potassium 

are very important in regulating the heart’s electrical impulses. Deficiency of these minerals predisposes one to SCA.

Testosterone helps modulate the flow of potassium in its channels and with magnesium protects against too much 

calcium channel infiltration. Low testosterone is associated with EKG irregularities. Men with higher levels were 23% 

less likely to suffer SCA while men with higher estrogen levels were twice as likely to suffer SCA.

An analysis of studies by the American Heart Assoc. in 2013 corroborated that low levels T are associates with some 

14 different health issues including: Type II diabetes, metabolic syndrome, belly fat, cardiac death, abnormal EKG and 

obesity among others. This review concluded: “Low testosterone levels have been shown to be associated with higher 

levels of all cause and cardio vascular related mortality.” “In addition, the severity of coronary artery disease and CHF 

correlates with the degree of testosterone deficiency.” The conclusion: Testosterone replacement therapy improves 

insulin resistance, helps diabetics, and lowers risk of atherosclerosis.Men with a high risk of CVD usually have a 

greater propensity to convert testosterone to estrogen (aromatase). Excess estrogen (estradiol) causes blood platelets 

which increase the chance of clots.

A study in the Journal of the American Medical Assoc. found that men under the lowest estradiol level were 317% 

more like to die from CVD and men above the highest level 133%. The balanced level for estradiol is 22 to30 pg/mL. 

This shows how important it is to have estradiol blood levels checked when contemplating Testosterone therapy. If 

the reading exceeds 30 simple steps can be taken to lower it. Many men have found that inches can be taken off their 

waist line by using testosterone therapy. Abdominal fat increases the conversion of testosterone to estrogen caused 

by the enzyme “aromatase”. Higher Testosterone levels DO NOT cause prostate cancer.

The next article is on BPH (enlarged prostate), ED (erectile dysfunction) and finally the therapy and supplements to 

help correct all we have talked about in these articles.

Testosterone's Medical Uses Part 2

TESTOSTERONE’S MEDICAL USES

This is the first of 5 reports on men’s health. This report is an outline of the 4 to follow. My original report on 

testosterone was published in the Atencion 3years ago. A lot of new research has been added to the 4 articles to 

follow.

These male health issues are all RELATED

TESTOSTERONE & GENERAL HEALTH

TESTOSTERONE &YOUR HEART

BPH (prostate enlargement)

ED (erectile dysfunction)

SOLUTIONS/ REMEDIES/ SUPPLEMENTS

If you do not want to receive these reports please send me an e mail

Thank You

Ross Macdonald

TESTOSTERONE ET.AL 

TESTOSTERONE IS AN ANDROGENIC SEX HORMONE PRODUCED BY A MAN’S TESTICLES, 

AND TO A LESSER DEGREE, IN SMALLER AMOUNTS, BY THE OVARIES IN WOMEN. WHILE 

TESTOSTERONE IS STEREOTYPICALLY ASSOCIATED WITH VIRILITY, IT ALSO PLAYS A 

ROLE IN MAINTAINING MUSCLE MASS, BONE DENSITY, RED BLOOD CELLS, AND A 

GENERAL SENSE OF WELL-BEING.

Recent research studies from major universities and health organizations show that low or high testosterone levels 

are detrimental to several aspects of men’s health. Testosterone is measured at two levels —bonded and free---the 

latter being the active form. Bonded testosterone makes up about 90% of the total and is bonded to bones and 

muscle. Free testosterone flows in the blood and is very important for many health aspects in men and women.

Metabolic Syndrome is a combination: -waist size, high blood pressure, high cholesterol, and high blood sugar. It 

leads to diabetes, heart disease and the inability to process fats and sugars. Men with low testosterone have an 

increasing prevalence of diabetes, hypertension, stress, and body fat (especially visceral belly fat). As total 

testosterone levels rise to the optimum level, (550ng/dl) or above, the chance for these diseases decreases. 

The important consideration is hormone balance. As men grow older they are more and more at risk for increases 

in an enzyme called aromatase. One of the main causes of this increase is belly fat. Obesity can cause estrogen 

levels to rise because belly fat produces aromatase which coverts testosterone into estrogen. 

When testosterone and estrogen are in youthful balance there are many protective effects. Research has shown 

there is an increase in mortality when estrogen levels are either too low or too high.

Measuring FREE testosterone is the most accurate way of assessing levels in men. The balance should be 20-

25ng/dl free with estrogen less than 30ng/dl. An in balance between these two hormones leads to diet resistant belly 

fat which is due to either too much estrogen or too little testosterone. In men this fat increases estrogen resulting in 

memory loss, lack of motivation, depression and low libido. Belly fat can also be linked to stress which releases 

hormones like cortisol which signals the body to maintain its fat and weight and also to low DHEA (the precursor 

to these hormones).

Low testosterone which may be linked to stress, can also lead to belly fat in both men and women. This type of fat 

resists diet, is very difficult to remove and can increase estrogen levels. This jump in estrogen levels helps to 

develop platelet aggregation, coagulation and inflammation in arteries which may cause a heart attack. The 

The Journal of the American Medical Assoc. published a study measuring estradiol (the active form of estrogen) in 

men with chronic heart failure (CHF). The end results were: men with the lowest level were 217% more likely to 

die and men in the highest level were 133% more likely to die sooner from all sources than men with a balanced 

estradiol—testosterone level. 

Now you know what belly fat,obesity can do.

References: 

Harvard Medical School Publications

Testosterone for Life , Testosrerone for a Quality Life, The Truth about Men and Sex; Dr Abraham Morgentaler, 

Harvard Medical School

 N.E. Journal of Medicine

Journal of the American Medical Assoc.

Journal of the American Heart Assoc.

Center for Science in the Public Interest, Michael Miller MD, Prof., Un. of Maryland 

Stanford Medical School

RB&E (online)

Consumer Labs

Life Extension Foundation. Philip Lee Miller,MD

Un. Of Texas Health Science Center

Johns Hopkins University Medical School

Scientific American

Boston University Medical School

ARTICLES

J. Mercola MD

Willaim Davis MD

Ray Shealin MD

Mark Moyad MD

Ross B. Macdonald January ,2016 121 1019; 415 153 5378, 

extendinglives@gmail.com;www.extendinglivesmexico.com

Smart Vitamin Buying

There are more than 1600 hundred vitamin/supplement brands in the USA made by fewer than 20 companies So prices are set by the type of marketing i.e. on line, retail stores, Drs web pages, MLMs (multi level marketing) and giant retailers’ private labels. Specifically ,a large vitamin manufacture which makes 18 different brands (all well recognized) with each having its own marketing. The products sold on line and the ones sold in the retail store have different brand names BUT the same inventory number, same strength, and same number of pills. However, the store brand is twice the price of the online brand.

Consumer Labs in New York, is the company that tests vitamins/supplements for quality, content, purity, ads, and price comparisons. The following is a quote from Consumer Labs after completing a massive survey of prices vs quality.  “ You certainly don’t need to pay the highest prices to get good quality supplements. In fact, Consumer Labs has found that some of the most economical products costing pennies per day are of better quality than premium priced supplements costing more than a dollar a day.”

Examples: cents per pill (same strength and number of pills)
- Co Q 10 9 vs 78      
- Lutein 9 vs 119    
- Magnesium 2 vs 83      
- Vit C 3 vs 78    
- Vit D3 4 vs 37  
- Fish Oil 5 vs 105

Consumer Labs’survey with answers from 10000 members  covered more than 1600 brands for popularity. It showed Life Extension Foundation to be the most popular overall. Others: Calcium and CO Q 10: Puritan Pride; Fish Oil and Multi Vit; Life Extension Foundation. Most popular on line retailer:  Swanson.

Vitamins are usually made from rock or coal tar and others are grown in nutritionally saturated water using plants like mustard seeds.  Calcium and Magnesium etc. are elements and cannot be changed chemically. Yes you can add to their structure (like Magnesium oxide or citrate)  or add additives but it has not changed the element itself. So vit C  is Vit C  without additives.

In my opinion on line Drs and MLM companies are the last place to buy supplements. They are rarely tested by Consumer Labs and probably do not have their own manufacturing facilities. These supplements are sold based on the doctors’ online reputation at very high prices. Some are made in China.

Supplements can be delivered anywhere in Mexico.

Testosterone's Medical Uses

Recent research studies from major universities and health organizations show that low or high testosterone levels are detrimental to several aspects of men’s health. Testosterone is measured at two levels —bonded and free---the latter being the active form. Bonded testosterone makes up about 90% of the total and is bonded to bones and muscle. Free testosterone flows in the blood and is very important for many health aspects in men and women.

Metabolic Syndrome is a combination: -waist size, high blood pressure, high cholesterol, and high blood sugar. It leads to diabetes, heart disease and the inability to process fats and sugars. Men with low testosterone have an increasing prevalence of diabetes, hypertension, stress, and body fat (especially visceral belly fat). As total testosterone levels rise to the optimum level, (550ng/dl) or above, the chance for these diseases decreases.  New research now shows that men in the lowest testosterone level are twice as likely to have cardiovascular disease (CVD) versus those at the optimum level who over the five year program had a 30% lower risk of CVD. Any level below 550ng/dl resulted in a significant increased risk. Only at 550ng/dl or higher was the 30% reduction for CVD seen and 24% for strokes.

The important consideration is hormone balance. As men grow older they are more and more at risk for increases in an enzyme called aromatase. One of the main causes of this increase is belly fat. Obesity can cause estrogen levels to rise because belly fat produces aromatase which coverts testosterone into estrogen. 

When testosterone and estrogen are in youthful balance there are many protective effects. Research has shown there is an increase in mortality when estrogen levels are either too low or too high.

Measuring FREE testosterone is the most accurate way of assessing levels in men. The balance should be 15-20ng/dl free with estrogen less than 30ng/dl. An in balance between these two hormones leads to diet resistant belly fat which is due to either too much estrogen or too little testosterone. In men this fat increases estrogen resulting in memory loss, lack of motivation, depression and low libido. Belly fat can also be linked to stress which releases hormones like cortisol which signals the body to maintain its fat and weight and also to low DHEA (the precursor to these hormones).

Low testosterone which may be linked to stress, can also lead to belly fat in both men and women. This type of fat resists diet, is very difficult to remove and can increase estrogen levels. This jump in estrogen levels helps to develop platelet aggregation, coagulation and inflammation in arteries which may cause a heart attack.

 High HDL levels (good cholesterol) protect against heart attacks by helping to remove plaque from arteries. Testosterone enables HDL to remove this built up of cholesterol from arterial walls and cycles it back to the liver for disposal. This is known as Reserve Cholesterol Transport (RCT). Adequate levels of testosterone are required for optimal support of this process; low levels may cause a drop in HDL increasing the chance of CVD. 

A major research study revealed that free testosterone levels below 17pg/dl resulted in a 3.3 fold greater risk in developing arterial disease. In perspective aging men with levels below 17pg/dl often have HDL levels below 40-50 mg/dl.

Chronic heart failure (CHF) is characterized by exercise intolerance, shortness of breath and muscle wasting. Low testosterone is one of the mail culprits. Testosterone increases anabolic function, improves arterial dilation and is a known anti inflammatory agent.

The Journal of the American Medical Assoc. published a study measuring estradiol (the active form of estrogen) in men with chronic heart failure (CHF). The end results were: men with the lowest level were 217% more likely to die and men in the highest level were 133% more likely to die sooner from all sources than men with a balanced estradiol—testosterone level.

Over 16 years ago several research reports indicated that excess estrogen (in its active form of estradiol) contributed to atherosclerosis (artery blocking). Men with only slightly increased levels had twice the risk of a stroke and a higher chance of CVD. The research also explained that men with “high” levels of estrogen and “low” levels of testosterone had higher incidences of benign prostate enlargement (BPH) . On the other hand too low estrogen levels can lead to osteoporosis and bone fracture.

A low testosterone level indicates an increased possibility of prostate cancer. This is detailed in research from Harvard Medical School with Dr. Abraham Morgentaler’s  book and from the National Institute of Health (NIH) 2006 ,It is high levels of estrogen not testosterone that cause prostate cancer. WHY?          

First: the research done in 1940 which stated that testosterone was the culprit (for which the author received the Noble Prize) was based on the results from dogs, a castrated man and ONE normal man! Dr Morgentaler’s research at Harvard starting years ago has proved this research was flawed.

Second: it was found that in aging men obesity, especially belly fat, can cause estrogen levels to rise. This visceral fat produces an enzyme called AROMATASE , which converts testosterone into estrogen. Excess estrogen is also one of the leading factors in women’s breast cancer.

New research just released from Un. of Texas Health Science Center : “ For the first time we have demonstrated that excess fat (adipose belly fat) is a key factor in cancer progression regardless of the diet contributing to the excess weight.”

Harvard Medical School list the optimum hormone levels as: DHEA -350-490ng/dl;  Estradiol 20-30pg/ml; Total testosterone 550/700ng/dl; free 20-25 pg/dl.

Abdominal exercises like sit ups and crunches do NOT reduce belly fat. This fat is deep and wrapped around your interior organs and is not affected by abdominal exercise. Exercises to reduce this visceral fat include: cardio, pushups, lunges, squats and step ups.

Now you will understand that belly fat is dangerous in more than one way

Erectile dysfunction (ED) is closely related the vascular disease. The three known common medications (Viagra et.al.) do not increase blood flow they activate an enzyme called FDN3 which inhibits the blood from flowing out. Researchers from Harvard have written several articles /books about ED, its’ probable causes and remedies. There are several non prescription items that have a proven beneficial record of alleviating ED. 

Erectile Dysfunction (ED) is caused by a lack of blood flow which can occur gradually as one gets older. It is closely related to CVD which may happen two or three years after the beginning of the ED. The three known common medications (Viagra et.al.) do not increase blood flow into the penis (however there are supplements that do so don’t worry) they activate an enzyme called FDN3 which inhibits the blood from flowing out. Researchers from Harvard and Life Extension Foundation have written several articles and /books about ED, its’ probable causes and remedies. There are several non prescription supplements that have a proven beneficial record of alleviating ED. 

Viagra et al (especially the daily dose of Cialis) has also been shown to reduce the urinary tract problems associated with BPH( benign prostate hyperplasia) and reduces stress in the brain after a stroke by stimulating the growth of nerve cellsThere are also remedies that inhibit aromatase from converting testosterone to estrogen. 

Essential Oils: What Are They? What Do They Do?

When a Supplement is called “Essential”   it means that the body does not produce it and, therefore, it has to be “supplemented” by other means—mostly by mouth.

There are several OILS (called fatty oils) that are important to your health. For one thing the brain is largely made up of these fatty oils. The “oil” known as Omega 3 is usually derived from cold water fish specifically mackerel, herring, halibut and salmon, or from Flaxseeds.( Many of you will remember being “forced” to take cod liver oils as kids). Omega 3 is a combination of EPA and DHA oils (the scientific names I will not bother you with). 

More and more strong evidence suggests that Omega 3 is one of the, most helpful supplements in your heart’s health  in the growth of cells, and in your immune and nervous system. Omega 3 comes in capsule form with a recommended dosage of 1000mg twice a day. Flaxseed oil has the added benefit of helping to maintain present cholesterol levels.

The Omega 6 oils come from Borage, Evening Primrose and Black Current oils. These are also essential and have successfully been used to combat  pain due to arthritis in its different forms. The base of Omega6 oils are grains and cereals. Omega 3 and 6 have been studied extensively and good results have been obtained using them to improve: age related mental impairment, Alzheimers, anticancer treatments, breast cancer, herpes, prostate cancer prevention and pain management, AND help maintain strong bones.

This is one of the most important supplements available. The various names are: DHA, EPA, OMEGA3, OMEGA 3,6,9.,FLAXSEED, AND GLA. Omega 3 oils should be accompanied by vitamin gamma E.

VITAMIN E is one of the most important antioxidants necessary to good health. . There are, however, various forms of this vitamin. The prefix “dl” states the vitamin is chemically produced, “d” is the natural form and is absorbed much more rapidly into your system.  Some research has found the synthetic Vit E is almost worthless. There are also the Alpha and Gamma forms. The considered best is Gamma Tocopherol a combination of both alpha+gamma tocopherols and tocotrienols.

Vitamin E works well with vitamin C and Selenium. It is a strong anti oxidant to fight free radicals in the body and helps maintains a healthy immune and prostate system. 

Several years ago at the Un of California Berkley researches discovered that old almost dying rats could be revived by using a form of the amino acid L- Carnitine ( used for heart health)  known as Acetyl L Carnitine (ALC). It was discovered that ALC slowed the breakdown of the animal’s cells – a real anti aging sign—and when the addition of a very strong anti- oxidant called Alpha Lipoic Acid( ALA) was added the rats remained  healthy. ALC is also widely known as a protector of brain cells.

ALA also promotes muscle energy, liver health, and revitalizes the underlying skin structure so it looks more radiant. ALA also has the ability to “recycle” the anti oxidants Vitamins C, E and Co Q -10 to help fight free radicals.

How Important Is Lifestyle?

Most of us are born with the potential to live a normal lifespan. What we do with and to ourselves in the ensuing years is our responsibility. The normal or convenient belief is that we have no control over risk factors, fate and our ancestors have fixed us with a definite genetic makeup. However, research indicates that genes play a significant but much smaller role and lifestyle a larger role. We determine our own fate throughout our entire life. Sickness is not a factor that has to occur in the elderly any more than  loss of mobility. Our problem is that we did not know the benefits of exercise and nutrition years ago. There is no time like the present!

Medical research has developed a new perspective on aging. Illnesses associated with age have little to do with years or getting older and much more to do with the accumulation of hidden health violations made in your earlier years. Apparently the experts are saying that despite the great health physical you just passed with flying colors you may still be at serious risk for eventual illness. However, at any age you have more control over your health than you may think and your lifestyle is one of the most important (if not the most important) factors in your fate.  

High blood pressure, increased blood sugar levels and excess weight are not, according to many experts, a normal part of aging. They are a result of the past and a sure sign of impending problems. Even at a late age these conditions can be ameliorated by a change in lifestyle---your body is quite resilient and muscles have memories --- it takes work. Physical and mental control over your life can even help you live longer; it certainly makes it easier to do so. Whatever your age you are NOT too old to exercise. Remember: “if you do not have time for exercise then make time for illness.”

Fat and strong bones are at war with each other. Even when you exercise regularly why don’t you lose fat?  Look at how and what you eat/. Processed and convenience foods have replaced raw foods. Fat free foods are not fat free to the extent you think. It still comes down to calories, the amount of sugar in your diet and how efficient your metabolism is. If your metabolic rate burns all day with regular small meals you will lose weight when combined with exercise. If it gets a big food splurge twice a day it will turn your body into fat, exercise or not. It becomes impossible to lose weight under these circumstances. It is becoming very apparent that sugar and corn fructose are the main cause and these high sugar foods are the secondary cause of several illnesses. Even carrots and beets are fairly high in sugar.

 Another old age problem is bone loss. We all know about 1,200-1,500 mg of calcium and 2-5000 mg of vitamin D3 and should know about vitamin K and DHEA taken daily. By the time you are in your 40s you are probably losing more bone mass than you are growing. “Any exercise will have a positive effect on bone density, but strength training yields the greatest results” A recent review of 22 well designed studies clearly showed the positive effects of weight training particularly for the elderly and postmenopausal. These benefits are twofold: 1) stronger muscles that provide stability and prevent falls and 2) stronger bones that resist fracture in the event of a fall.

It is so easy-- all you need is the will to live.

Omega 3 Oils

People age prematurely due to oxidation and glycation. Antioxidants help control the former

( vitamin E,C,GREEN TEA etc) they are not helpful with glycation which causes sugars to link with proteins which degrades the function of the proteins. The amino acids L- Carnosine and L-Taurine in combination with vitamin B1 inhibit the pathways involved in the sugar toxicity to the cells.

 FISH OIL,  WHAT IS IT?  This supplement known under the names:Omega 3, Essential oil,  Salmon Oil, Krill  is basically derived from cold water fish like salmon, mackerel, and tuna. It has been recognized for years for its strong ability to protect against cardiovascular disease and now in depth research has added remarkable new attributes to fish oil: guarding against depression, cancer, osteoporosis, and arthritis among others. These simple oils became so important that one drug company “persuaded” the Federal drug Administration ( FDA) to approve a fish oil drug called OMACOR which will sell for over $250.00  or about 12 times what you pay for Omega 3 in the store.

The American Heart Assoc now endorses Omega 3 fatty acids to lower triglycerides, reduce heart arrhythmias and slow plague growth. Fish oil also clears the fat from the blood after a meal. Scientists suspect this fat a contributor to atherosclerosis. Studies show that Omega 3s slow the rate of plaque growth, This plaque can cause sudden heart attckes without warning. In fact it is believed tha Omega 3 actually changes the composition of the plaque making it less likely to rupture.

In addion, these fatty acids can help dilate blood vessels helping the blood flow.

 Fish oil also suppresses abnormal heart rhythms In one study eating one or more servings of old water fish per week reduced the risk of sudden cardiac death by 52%!!

Cold water fish oils are EPA and DHA. A much less concentrated source is Flaxseed oil and Canola oil. These should not be considered in the same heart disease fighting category as the Omega 3 oils.

 CANCER: Omega 3 oils are now used to fight cancer. These oils alter genetic signaling in cells preventing them from becoming cancerous and “reprogram” damaged genes so they cannot contribute to the start of cancer. Fats called Omega 6 fats from vegetable oil, eggs and poultry

contribute to the growth of pro-inflammatory compounds; the Omega 3 oils produce anti inflammatory compounds.

EPA and DHA have prevented the progression of breast and prostate cancer cells in both laboratory and animal studies. Also the Omega 3 fatty acids can inhibit receptors on the cells that are needed for tumor cells to grow. Other studies show that the Omega 3s have a powerful ability to reduce the risk of prostate cancer and breast cancer.

For over 10 years doctors have known that Omega3 can shield your skin from harmful sun rays and sunburn!

DEPRESSION: New compelling evidence shows that mental health disorders such as depression, attention deficit disorder, and schizophrenia may reflect a severe lack of Omega 3 fatty acids.

The low fat craze can cause depression; Omega 3  fight depression and enhance the action of other drugs. The fatty acids fight depression in doses of 2000 to 4000 mg per day. 

More than 1/3 of the brain’s fat is Omega3 fatty acid. A deficiency of these fats can decrease the blood flow to the brain.

BONES: Research now understands that Omega3 fats improve bone structure by increasing calcium absorption ,reducing bone loss, and maintaining mineral density. They may prevent age related declines in bone mineral density while increasing the intake of calcium.

ARTHRITIS:  . New ssubstances from EPA and DHA called “resolvins” and “protectins” may relieve pain, inflammation and immobility associated  with arthritis without any side effects.

Sarcopenia

SARCOPENIA: What’s this? Severe loss of muscle mass as you grow older without a proper regimen.

This program should include: dietary modifications, hormone replacement therapy, nutritional supplements, vitamins, and EXERCISE. This will dramatically improve lean muscle mass at any ANY AGE.. This program should begin now.    Now is better than later!!

Age related loss of muscle increases the risk of devastating injuries and death from sudden falls and other accidents. San Miguel is a perfect example of this.

This disease starts after age 40 and increases rapidly after 75. While engaging in physical activity is essential, inactivity is not the only factor. Like osteoporosis sarcopenia is a multifactorial disease that may result from suboptimal hormone levels, inadequate dietary protein, nutritional imbalances lack of exercise, oxidative stress and inflammation.. Sarcopenia and osteo are related conditions and one often follows the other. Muscles generate the stress required to keep our bones strong. .When muscle mass is reduced it increases the loss of bone mass.

 Muscle mass also acts as a metabolic reservoir. For example, after a traumatic event muscles produce proteins and metabolites required for survival and recovery. NOW this suggests that elderly people lacking this metabolic energy due to low muscle mass will have a harder time recovering from operations AS THEY LACK THE MUSCLE TO SUPPORT THE IMMUNE SYSTEM

Dietary factors that contribute to sarcopenia  are: inadequate protein intake, calorie intake, and abnormal acidity in the body’s fluids.. Older adults seem to have a low intake of protein perhaps due to an inability to digest it. Protein requirements for seniors are higher than for younger people, AND should be higher than most doctors recommend. But it’s also true that too much protein can cause acidity. So a buffering agent can be used to allow higher protein intake and decrease acid. THIS IS Potassium Bicarbonate.

Hormone levels must be maintained. The important ones are HGH (human growth hormone) ,DHEA, TESTOSTERONE, Mecanico growth factor and insulin-growth factor. Without these basic hormones it may be impossible for anyone to maintain lean muscle mass regardless of what they eat or exercise.

Adequate levels of testosterone in older men are Essential, and to a lesser extent in women. (who can use DHEA), Everyone over 40 should have a hormone balance test yearly. 

To combat sarcopenia the best supplements are Creatine, vitamin D3, and WHEY protein. Creatine helps replace APT, the chemical necessary for fast “twitch” muscle reactions. Creatine when given to older men and women in resistance training (weights) increases strength and muscle mass. (Creatine is the supplement most used by professional athletes).Vitamin D3 helps preserve the Type II fibers that are the ones prone to atrophy in the elderly. Low vitamin D levels are associated with poor bone formation and muscle mass.

WHEY PROTEIN: contains the amino acids necessary for the development of protein in the body and muscles.

OTHER NECESSARY SUPPLEMENTS:  Omega3 (fish oil, DHA and EPA) ,L-Carnitine ,especially the acetyl variety,and, in particular, L-Glutamine  the most abundant amino acid in the body and  muscle and necessary for the immune functioning of the digestive tract.

EXERCISE is critical!! It stimulates the release of hormones like HGH, human growth hormone, and mechano hormone.  Aerobic exercise is great for the cardiovascular system and body fat. BUT it is not very effective in preserving lean muscle mass. Athletes use weight training when they want to increase lean muscle mass. The federal Center for Disease Control notes that in addition to building muscle mass, strength training can promote mobility, improve health related fitness and improve bone health.

Skin

The skin is the largest organ in your body, comprising several layers of tissues. Skin protects against germs, provides insulation, temperature regulation, and sensation and helps synthesize Vitamin D (a hormone)from the sun. . Years of free radical damage can cause changes in the skin’s appearance. The final result of these age related changes is wrinkling, dryness, sagging, lost flexibility, dullness and poor healing.

The aging process in all areas of the body from brain to toes is a result of decreasing mitochondrial activity. These cells are the cellular power plants that produce energy. As we age this “power plant” slows down and in combination with the detrimental oxidative processes within our bodies causes aging. We cannot live with out oxygen but it also in the long run “burns” us up.

Cells called Fibroblasts produce the proteins named collengen and elastin which provide the underlying support for the layers of skin. As the mitochondrian in these cells dysfunctions they are no longer able to structure the skin and “olaha”,sagging, wrinkles and more. Sun,wind and dryness help the process along. So what can we do about it?

Start with the simple things:  WATER-- drink lots of it, take L Lysine and L Proline that is the least expensive and simplest formula. Then: (1) Use a sun screen rated for both UVA and UVB rays one without the other does not help; and put a cream lotion of Vitamin E on your face under it.

(2) As much as possible use a combination of Matrixyl 3000,ceramides,glycolicand hyaluronic acids, Co Q 10, green tea, promegranate and vitamins E and C used together both orally and topically. AND exercise your face. Yes , it’s a lot so let’s look at each one individually.

The sunscreens need to be qualified by the FDA as Category 1. They should contain Oxybenzone and Avobenzone along with Beta Glucan ( an oat derivative). Using this sunscreen along with daily application of Vitamin E and C skin creams is helpful. The screen should also have zinc or titanium oxide.

If you have dark age spots try Vitamins A, C ,biotin and bioflavonoids.

Matrixyl 3000 is a patented product the helps “lift” or plump up the skin layers. Thereby , minimizing the appearance of wrinkles and creases. Studies have shown that after 8 weeks of topical application the surface area occupied by deep wrinkles shrank by 45%. Skin tone improved by 20% during the same time frame.

Ceramides, found in good skin creams, are similar to those lipids that occur  in skin membranes. These ceramides or lipids maintain the protective functions of the skin’s outer layer.

Co Q 10 helps control “photoaging”. Photoaging produces negative changes in skin color, texture and health caused by exposure to ultraviolet light. CO Q 10 concentrations in skin decline significantly in older people .The loss of this agent is the probable  cause of the increases in skin diseases ( including cancer) and photoaging..A long tern study found a direct link between CO Q 10 levels and the progression of melanoma and its spread to other parts of the body.

Co Q 10 is widely used to counteract the decline in mitochondria energy that causes aging. Oral and topical use of this agent restores deficient levels in cells. It is best known as an anti oxidant for the heart.

 Idebenone or ubiquinol; a cousin of CO Q 10, is stronger and even better at conferring protective effects. It has been shown to produce clinically visible improvements in phototaged skin.

To avert many of the effects of ultra violet light topical applications of green tea, glycolic and hyaluronic acids promote skin texture and appearance. Green tea also enhances the cells’ responses to inflammation and chemicals that can cause tumor growth.